The propylene glycol family of chemical compounds consists of monopropylene glycol pg, dipropylene glycol dpg, and tripropylene glycol tpg. On burning will emit toxic fumes, including those of oxides of carbon. Pg60ml, pg120ml, pg250ml, pg500ml, pg1gal, pg5gal synonyms. Dow propylene glycol is used as a raw material for the manufacture of other chemicals and as an ingredient in product formulations. All these documents, with focus on pharmaceutical applications may serve as additional. Propylene glycol is a highpurity material, which must be handled with special precautions to avoid contamination. Ethylene glycol is a clear, colorless, odorless, sweettasting liquid. Dow propylene glycol is a viscous, colorless, odorless liquid. Remove contaminated, soaked clothing immediately and dispose of safely. Propylene glycol, propan 1, 2 diol, dowcal 20, dowcal n, 1, 2 propylene glycol care. Nsf has processed the application for registration of propylene glycol uspep to the nsf registration. Nsf international nonfood compounds registration program.
Identification of the substancemixture and of the companyundertaking date issued 04. First aid measures always seek professional medical attention after first aid measures are provided. Product identifier product name mono propylene glycol usp product number 31055 cas number 57556 ec number 2003380 1. Invalid emails will appear to work, but in reality we will not receive them. Propylene glycol usp the generation of waste should be avoided or minimized wherever possible. In order to access the atsdr toxicological profiles pdf files below, you must have adobe acrobat reader. Handle in accordance with good industrial hygiene and safety practice. Propylene glycol provides the rumen the precursors for the animal to create its own glucose, due to its fate in the rumen environment. Chemical product and company identification product name. Pg uspep is tested for compliance with the current united states pharmacopeia usp. Propylene glycols are sensitive to oxidizing agents, e.
Glycol is metabolized, metabolic acidosis and further central nervous system depression convulsions, muscle weakness develop. Physical properties units propylene glycol dipropylene glycol tripropylene glycol density gcm 3, 77f25c 1. Propylene glycol,us nsn 6505006873667 niin 006873667 procurement. Fire fighters to wear selfcontained breathing apparatus and suitable protective clothing if risk of exposure to vapour or products of combustion. Identification of the substancemixture and of the companyundertaking 1.
Exposures to propylene glycol having no adverse effects on the mother should have no effect on the fetus. Mono propylene glycol usp this sds is not mandated under reach regulation ec no 19072006 and is provided for information only. An alternative, albeit a temporary bandaid type fix and one that acts directly on the bloodstreams glucose level is intravenous dextrose or glucose allowed. Special hazards or target organ effects are given as a generic warning, substance specific data is not available. Nevertheless osmolar gap increases with increase in propylene glycol concentration and in general the correlation is strongest as lorazepam. Material safety data sheet page 1 of 2 propylene glycol. Just remember that it should be handled as though it were a food. Safety data sheet 1,3butylene glycol date prepared.
Safety data sheet page 1 of 6 may 11, 2017 section 1. Call a physician or poison control center immediately. Antifreeze breaks down over time and forms acids, which corrode the vehicles cooling system. Nsf international nonfood compounds registration program sandra kupperblatt dow chemical company, the united states midland, mi 48674 february 12, 2004 re. Propylene glycol used in animal drugs, feeds, and related products is generally recognized as safe except in cat food when used in accordance with good manufacturing or feeding practice. Box 4980 the woodlands, tx 77387 telephone numbers transportationemergency chemtrec. Pll, a global leader in filtration, separation and purification, today announced it has completed the acquisition of filter specialists, inc. Propylene glycol pg uspep is a pharmacopeiaspecificationsgrade excipient of monopropylene glycol pg or mpg with a specified purity greater than 99.
In animal studies, propylene glycol has been shown not to interfere with reproduction. Never give anything by mouth to an unconscious person. Safety data sheet ethylene glycol 100% inhibited page 3 of 10. No repeated inhalation exposure studies are available for tripropylene glycol or dipropylene glycol.
Download printerfriendly version adobe pdf file pdf 496. Identification of the substance preparation and of the company undertaking product identifier. Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Propylene glycol is a 3carbon compound derived from propylene which has applications in both industry and medicine.
Dipropylene glycol, fragrance grade is commonly used as a carrier for fragrances. During its use, antifreeze may become contaminated with traces of fuel, metal particles, and grit. Propylene glycol c3h8o2 cid 1030 structure, chemical names, physical and. Common name 1,3butylene glycol formula c 4 h 10 o 2 cas number 107880 component cas number concentration 1,3butylene glycol 107880 99. Reproductive effects this substance is not expected to be a reproductive toxicant. Under ordinary conditions, mild steel is a satisfactory material of construction. Propylene glycol used as an excipient european medicines agency. Material safety data sheet propylene glycol industrial grade august 17, 2011 page 3 of 6 handling and storage general. Meanwhile, 1,3 propylene glycol, named trimethylene glycol, is. Propylene glycol is included in pediculicide drug products. Dow propylene glycol uspep general description propylene glycol uspep pg uspep, referring to the united states and european pharmacopoeias, is a highpurity grade of monopropylene glycol for use in pharmaceutical, food, cosmetic, personal care, flavor and fragrance, plus a variety of other applications.
First aid measures general advice consult a physician. Ethylene glycol industrialethylene glycol meglobal glycol solv ethylene glycol, section 4. Technical data propylene glycol specific gravity of aqueous propylene glycol solutions gravity chart specific gravity of aqueous propylene glycol solutions 1. Propylene glycol glycol, 1,2 propandiol 57556 99 100% 2017. Have victim rinse mouth with water, then give one to two glasses of water to drink. Ethylene glycol industrialethylene glycol meglobalglycolsolv ethylene glycol, section 4. Propylene glycol safety data sheet according to federal register vol. Propylene glycol is used as a drench in the treatment of ketosis.
Dispose of surplus and nonrecyclable products via a. Drug products containing certain active ingredients offered over the counter otc for certain uses. Safety data sheet monopropylene glycol page 1 issued. Chemtrec 8004249300 outside usa 7035273887 1216 6th ave n kent wa 98032 phone. As such, they attract and hold water when exposed to the environment. This material and its container must be disposed of in a safe way. Safety data sheet monopropylene glycol mpg section 1. Boiling point of aqueous propylene glycol solutions. Show this safety data sheet to the doctor in attendance.
Safety data sheet propylene glycol usp wizard labs. Propylene glycol usp proper handling page 2 of 3 if good hygienic practices are followed and the recommended materials of construction are used, the handling of propylene glycol usp should be no problem. Propylene glycol 000057556 95% na dipotassium phosphate 007758114 sheet. Propylene glycols are hygroscopic liquids and efficient humectants. Chemical of the day todays chemical propylene glycol. Empty containers or liners may retain some product residues. Special hazards arising from the substance or mixture fire hazard. Show this safety data sheet to the doctor in advance. Propylene glycol 9095 ne ne 57556 na not applicable ne not established section iii physical data boiling point f. Product identifier product name monopropylene glycol mpg chemical name 1,2propylenglykol reach reg no.
Heating may cause a violent combustion or explosion producing toxic fumes nitrogen oxides. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Immediately flush eyes with excess water for 15 minutes, lifting lower and upper eyelids occasionally. Revision bulletin 2 propylene official february 1, 2010 ature is 250, and the column temperature is programmed at a rateprocedureinject a suitable volume, typically about 10 l, of of 5 per minute from 120 to 200, and helium is used as the car propylene glycol into a suitable gas chromatograph, and record the. Firstaid measures description of first aid measures do not induce vomiting. An expert panel convened by the ntps center for the evaluation of risks to human reproduction concluded 23 that developmental and reproductive risks stemming from exposure to the chemicals propylene glycol and ethylene glycol are negligible. Ethylene glycol and propylene glycol have similar physical properties and uses. Material safety data sheet validation date product and company identification 1. Propylene glycol, among other things, is a penetration enhancer, meaning its a carrier for other chemicals, bringing them into. It has low vapor pressures at room temperature and, therefore, low potential for significant inhalation exposure. May also decompose explosively from shock, friction or from a buildup of electrostatic charge that sparks suddenly to ground. Dipropylene glycol, industrial grade dpg, with almost identical properties, is frequently used in resins and cleaner formulations where low odor is.
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